Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Homo sapiens | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
von Willebrand factor + H2O | Homo sapiens | persistently elevated levels of von Willebrand factor in plasma during and after liver transplantation, while plasma levels of ADAMTS13 dropp during transplantation | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
plasma | persistently elevated levels of von Willebrand factor in plasma during and after liver transplantation, while plasma levels of ADAMTS13 dropp during transplantation | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
von Willebrand factor + H2O | - |
Homo sapiens | ? | - |
? | |
von Willebrand factor + H2O | persistently elevated levels of von Willebrand factor in plasma during and after liver transplantation, while plasma levels of ADAMTS13 dropp during transplantation | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ADAMTS13 | - |
Homo sapiens |
vWF-cleaving protease | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
additional information | development of a severe von Willebrand factor/ADAMTS13 dysbalance during orthotopic liver transplantation, overview | Homo sapiens |
physiological function | von Willebrand factor, VWF, reactivity is regulated by a VWF-cleaving protease, ADAMTS13. A temporary ADAMTS13 deficiency during liver transplantation might contribute to postoperative thrombotic complications | Homo sapiens |